2.6-year-old woman presents to the clinic for evaluation ofa red rash small over joints
10 cheeks and pain, and swelling in both wrists, as well as several
ner hands. She notes that the rash gets worse on sun exposure and involves
sun exposure
worse
her cheeks, nose, ears, and chin. Medical evaluation reveals a facial rash with
nasal fold sparing, oral ulcers, and 3+ proteinuria. Which of the
following is
the MOST specific test for diagnosis of this condition?
A. lupus erythematosus (LE) cells
B. antinuclear antibody (ANA)
€. anti-Sm antibody
D. anti-Ro antibody
E. antiphospholipid antibody