After leaving Ethereum in 2014 Charles Hoskinson and Jeremy Wood set out their plans for Cardano in 2015.[9][10][11] Hoskinson had left Ethereum after a dispute with another co-founder, Vitalik Buterin. Hoskinson wanted to accept venture capital and create a company, while Buterin wanted to keep it as a nonprofit organization. Woods and Hoskinson co-founded the business IOHK to develop blockchains for use by corporations, governments, and education institutions.[11]

Cardano was initially released to the public in 2017.[3] That year, IOHK partnered with the University of Edinburgh to launch the Blockchain Technology Laboratory.[12][13] The lab had six post-doctoral and professorial positions with up to 35 jobs created in total, and was led by Aggelos Kiayias, developer of the Ouroboros protocol.[14]

Cardano reached a market cap of $77 billion in May 2021, which was the fourth highest for a cryptocurrency at that time.[15][16]

Advertising agency MBLM ranked Cardano 26th for brand intimacy out of 600 brands in August 2022, in between Ford and Nestlé and the highest rank for a cryptocurrency. Citing an MBLM partner, advertising industry magazine Ad Age said Cardano's high ranking "can likely be chalked up to the gambling element of crypto".[17]#cordano

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