BIO traders use a wide range of trading signals and technical indicators to predict the trajectory of a price. While not all methods are necessary to accurately predict the direction of the market, some key indicators carry more weight. Identifying Bio Protocol support and resistance levels gives traders insight into the supply and demand of the market, while helping to determine trend reversals.

In addition, chart patterns are also widely used by traders to form trend lines that help predict the next candlestick movement.

A number of indicators, such as the RSI, Moving Averages, and MACD, can be used to determine the direction of the long-term trend and attempt to predict future price movement.