Choosing the best coin to trade on Binance depends on several factors, such as your market analysis, current news, and your trading strategies. Some popular coins include:

1. **Bitcoin (BTC)** - the most popular and stable.

2. **Ethereum (ETH)** - a smart contract platform with wide applications.

3. **BNB** - the native coin of Binance.

4. **Cardano (ADA)** - known for its smart contract capabilities.

5. **Solana (SOL)** - characterized by its fast transactions.

It is always advisable to do good research and analyze the market before making trading decisions.