Bitcoin investors may want to consider selling when profits hit a key level, according to CryptoQuant. Their analysis suggests that Bitcoin bull markets often end when supply profitability crosses a certain threshold. Historically, when the percentage of BTC supply in loss drops below 4%, it signals the peak of a bull run, indicating a good time to sell using dollar-cost averaging (DCA). Currently, the supply in loss is around 8%. Meanwhile, Bitcoin whales show modest unrealized profits, suggesting room for continued bullish trends in the mid-term. Always research before making investment decisions.