Cardano founder Charles Hoskinson predicts that Bitcoin's decentralized finance (DeFi) will outshine all other crypto DeFi ecosystems within two to three years. In a recent YouTube video, he highlighted Bitcoin's transformation from a "sleeping giant" to a major player, now larger than Solana and Ethereum combined. Hoskinson forecasts Bitcoin's price could soar to $250,000-$500,000 in the next 12-24 months due to increased investment interest. He also introduced a new model for integrating DeFi into Bitcoin via Cardano, allowing users to bridge Bitcoin to a wrapped token on Cardano for DeFi participation.