Golden Finance reports that Santiment stated on X that the average trading return can indicate whether it is truly the right time to buy low or sell high. Currently, active wallets over the past 30 days for BTC, ETH, ADA, DOGE, and the vast majority of altcoins are in a negative range. When MVRV is negative, it means buying or increasing positions while others are already at a loss. Historically, these 'blood in the streets' moments are when professional traders make money. Santiment advises investors to trade cautiously and not to assume that these opportunity zone signals will lead to an immediate turnaround. However, the likelihood suggests that cryptocurrencies may see an improvement at least in the short to medium term, provided that economic or geopolitical factors do not hinder momentum development.