On December 23rd, Binance announced that Binance Launchpool will launch its 63rd project BIO Protocol (BIO), with trading pairs like BIO/USDT and BIO/BNB opening on January 3, 2025. According to Binance's announcement, the total supply of the genesis token for BIO Protocol is 3,320,000,000 tokens, with an initial circulating supply of 1,296,529,168 tokens at the time of listing on Binance, accounting for approximately 39.05% of the total genesis token supply. Of these, 56% of BIO tokens will be allocated to the ecosystem and community, 25.4% to early contributors, and 18.6% to early supporters.
Since Binance Labs announced its investment in BIO Protocol, the DeSci market has reignited, with related concept tokens like VITA, GROW, RSC significantly rising. Following the news of Binance Launchpool, recently popular ecological meme coins also surged rapidly, with RIF briefly rising over 40%, URO briefly rising over 35%, and DRUGS briefly rising over 150%. Additionally, established DeSci tokens like VITA and RSC have started to show market reactions.
In this article, BlockBeats comprehensively outlines the current BIO ecosystem and potential targets related to the DeSci concept, from DAOs to NFTs and meme coins, indicating that there are indeed speculative opportunities in the DeSci field.
BIO Ecosystem DeSci DAO
BIO is a biological DAO network, where each biological DAO focuses on developing research and products in specific scientific fields. Currently, the BIO network consists of eight different scientific communities, focusing on longevity, women's health, neurodegenerative diseases, and synthetic biology, among other fields. The background and mechanism of BIO Protocol will not be elaborated upon further in this article.
Related reading: (Interpreting BIO Protocol: Launching on Binance; Gaining attention from CZ and Vitalik as the 'on-chain science version of Y Combinator')
Initial DeSci DAO
The initial DeSci DAO was established before the BIO Protocol split from Molecule, and there are currently 7. After the formation of the BIO Protocol, these DAO organizations were first incorporated into the BIO network. During the previous BIO Genesis Event, users had to exchange BIO tokens using the tokens of these DAO organizations, making these DAO tokens part of the BIO network assets.
VitaDAO: Raised over $5 million in the field of longevity science, is a DeSci decentralized scientific organization supported by Pfizer's venture capital division and Balaji Srinivasan, collaborating with Newcastle University. Notably, VitaDAO is the 'elder among elders,' the first DeSci DAO of Molecule, the mother of the BIO Protocol, focusing on research in the longevity field. The current BIO Protocol association is also a Swiss non-profit organization founded by key members of VitaDAO.
HairDAO: Targeting hair loss; DAO owns patents and consumer product Follicool.
CerebrumDAO: Promoting brain health, raised over $1.5 million and partnered with Fission Pharma to address mitochondrial dysfunction in neurodegenerative diseases.
ValleyDAO: Focusing on synthetic biology, raised over $2 million and collaborated with Imperial College London.
AthenaDAO: Promoting women's health R&D, providing $500,000 in funding for translational research, with 14 intellectual property transactions pending.
CryoDAO: Promoting the development of cryobiology, raised over $3 million in this field, establishing projects with Oxford cryogenic technology and advanced neurobiology.
PsyDAO: Focusing on psychedelic drugs, launched a new platform OPSY utilizing psychedelic drug trials and data.
First batch of Launchpad DAOs
BIO Protocol recently announced the first batch of Launchpad DAOs after its launch, with these DAOs being auctioned through the BIO platform's Launchpad mechanism. Among them, the first DAO to conduct a token auction is Quantum Biology DAO, which concluded its auction activity on December 17th, with bidding being very heated, and the starting price at one point exceeded the original price by more than ten times.
Long COVID Labs: Accelerating the cure for over 100 million Long COVID patients. Founded by Rohan Dixit, a former Stanford neuroscientist, healthcare entrepreneur, and Long COVID survivor.
Quantum Biology DAO: Creating quantum microscopes to advance biological research. Founded by Clarice D. Aiello (MIT Ph.D., world-leading quantum biology scientist) and Geoff Anders (Executive Director of Leverage Research).
Curetopia (Rare Diseases): Addressing the field of rare diseases valued at over $10,000 by uniting families and patient communities. Founded by Ethan Perlstein, a Harvard Ph.D., entrepreneur, and Y-Combinator alumnus.
BIO-related meme & AI DAO
In addition to serious scientific research DAO organizations, the BIO team and community have also conducted interesting DeSci experiments outside of DeSci DAOs, successfully bringing significant attention to the DeSci field.
RIF/URO
Pump.Science is a meme token platform launched by BIO Protocol at this year's Token 2049 Solana Breakpoint conference, allowing players to buy meme tokens representing drugs and participate in drug effect predictions and experimental data trading. The surge of RIF/URO after DEVCON Bangkok also directly ignited interest in the DeSci field, which has been viewed by the market as a leading speculation in the DeSci arena for a long time.
Related reading:
(DeSci leader is also getting creative; can Pump.science successfully play 'biological science memes'?)
(Biological experiment memes skyrocketing a thousand times in a week, hot money is flowing into DeSci)
(Latest interview with Pump.Science founder: After RIF and URO, what will be the next DeSci + meme?)
DRUGS
DRUGS (Big Pharma) is also known as 'Little BIO,' the 'favorite child' of the BIO Protocol ecosystem. DRUGS aims to disrupt the monopolistic business model of traditional large pharmaceutical companies, receiving widespread support from the BIO ecosystem from the outset, including Pump Science, other BIO-related DeSci DAOs, and BIO co-founder Paul himself.
Related reading: (The 500-fold wealth myth of DRUGS ignites a new wave of daos.fun IPOs)
GIRLE/BABY
GIRLE and BABY are AI DAO and meme tokens issued by AthenaDAO on the Solana DAOs.fun platform and Base chain, both supporting scientific research in the field of women's fertility.
Among them, GIRLE aims to empower the future of fertility through AI and Web3, and the team is currently conducting related experiments on peptide cell repair, testing the effects of peptides on cells, and will soon launch related experimental tokens. Their official website also shows the holdings of other tokens in the DAO treasury.
BIO Ecosystem IPT
IPT is the intellectual property token pioneered by the Molecule Catalyst platform, representing partial governance rights over generated research IP. These tokens allow holders to directly participate in research development, decision-making, and future directions. Each BioDAO typically holds a portfolio of IP tokens representing intellectual property related to specific scientific research areas of the BioDAO. Currently, the most recognized IPTs are the IPT VitaRNA and VITA-FAST developed and owned by VitaDAO.
IPT VitaRNA & VITA-FAST
VitaRNA is the IPT of Artan Bio, a gene therapy project that raised over $300,000. Artan Bio is exploring promising gene therapy fields that address genetic factors related to aging. The company's approach aims to develop therapeutic candidates that may inhibit mutations leading to aging. Artan Bio is led by two entrepreneurs who previously advanced a drug development platform to human clinical trials.
VITA-FAST is the IPT of Viktor Korolchuk's lab, which successfully raised over $300,000. VITA-FAST focuses on researching drugs that enhance autophagy, a natural 'waste disposal' mechanism built into our body cells that can eliminate unnecessary protein accumulation.
OVARIA
OVARIA is the IPT launched in collaboration between AthenaDAO and Gero. Gero is a biotechnology company using artificial intelligence for target and drug discovery. AthenaDAO collaborates with Gero to revolutionize the treatment landscape for ovarian aging, offering therapeutic potential in currently limited areas. AthenaDAO will use their platform to identify up to 10 new targets for ovarian aging, with trial results expected to delay menopause and reduce its health-related consequences.
Competition & related memes
In addition to BIO-related targets, the ecosystem's popularity has also extended to other areas of DeSci.
RSC
Research Hub is a DeSci project founded by Coinbase CEO Brian Armstrong, aimed at accelerating the pace of scientific research. By creating modern mobile and web applications, it allows people to conduct scientific research more effectively.
Within the ResearchHub platform, research papers are stored and grouped by research field in 'centers.' Individual centers essentially serve as live journals within focus areas, moving high-vote posts (i.e., papers and their related abstracts and discussions) to the top of each center.
Scihub
Scihub is inspired by the world's largest free paper download center Sci-hub, which faces legal issues due to open sourcing and relies solely on donations for maintenance. 0xAA (@0xAA_Science) is the top holder of this token, currently holding 22% of the total token supply, and he stated he would donate 20% of the tokens to SciHub's operators to support their cause and platform development.
Currently, BIO Protocol has announced its roadmap for 2025, including:
BIO token will have its TGE on January 3rd on the Ethereum mainnet;
BIO token will launch on Solana and Base networks;
New BioDAO launched;
BIO/BioDAO liquidity pool;
The new BIO Launchpad has officially launched.
With the BIO token launching on Binance, the DeSci field may welcome a new wave of excitement.