Some of the cryptocurrencies that are popular and have profitable potential include:

1. **Bitcoin**: It is the first and most popular cryptocurrency, and is often of interest to investors.

2. **Ethereum**: It supports smart contracts and has a wide ecosystem of decentralized applications.

3. **Binance Coin**: The currency of the Binance platform, and has seen significant growth.

4. **Cardano**: It is known for its scientific orientation and sustainable development.

5. **Solana**: It is known for its high speed and low transaction costs.