With the involvement of Binance and a16z, the DeSci field is rapidly heating up. Many DeSci tokens are expected to achieve 100x growth in the future. Today, we will delve into the concept, solutions, application scenarios, and some potential projects worth paying attention to in DeSci.

I. What is DeSci?


DeSci stands for Decentralized Science, which aims to fundamentally transform the traditional scientific research (TradSci) methodology through blockchain technology, addressing three core issues:

1. Restricted Research Access: Research findings are often hidden behind high subscription fees.

2. Slow and Bureaucratic Funding: The traditional funding system is inefficient and constrained by administrative barriers.

3. Limited Global Collaboration: Scientific innovation is obstructed by geographical and institutional barriers.

The goal of DeSci is to create a transparent, censorship-resistant, and open scientific ecosystem through technological means, accelerating global scientific progress.

II. Solutions of DeSci

The traditional scientific research ecosystem has many pain points. Funding allocation is highly concentrated, often leaving only a few well-known institutions and top scholars with sufficient research funding. The academic publishing ecosystem is closed and costly, with researchers needing to pay to publish papers, while journals and publishers rake in huge profits. The peer review process lacks transparency and is susceptible to subjective bias. Furthermore, shared research data is difficult, and intellectual property protection is inadequate, severely limiting the innovative vitality of scientific research.

DeSci addresses the inherent issues of TradSci through the following methods:

  1. Decentralized Research Ownership: Scientists and the community jointly control the research process and intellectual property.

  2. Efficient Funding and Governance: Utilizing DAO (Decentralized Autonomous Organization) model to directly connect funders with researchers.

  3. Open Publishing Mechanism: Abandoning traditional paywalls to allow research findings to be disseminated and shared more freely.

These innovative mechanisms empower scientists while incentivizing community participation, driving scientific research to be more efficient and equitable.

III. Application Scenarios of DeSci

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DeSci has already seen extensive practice in multiple fields, including:

  1. Research Funding: VitaDAO: Allowing the community to directly fund longevity research through a DAO model, circumventing traditional funding barriers.

  2. Data Ownership: GenomesDAO: Allow individuals to control genomic data, ensuring privacy while benefiting from data sharing.

  3. Academic Publishing: ResearchHub: Rewarding open-access research papers, eliminating paywalls, and enhancing academic dissemination efficiency.

  4. Medical Innovation: DataLake: Creating a secure patient data sharing platform to promote medical breakthroughs while protecting privacy.

  5. AI and Data Collaboration: OriginTrail: Providing a decentralized knowledge graph for AI and machine learning applications.

  6. Synthetic Biology: ValleyDAO: Funding synthetic biology research to address climate challenges and promote sustainable development.

IV. DeSci Bullish Catalysts

The rise of DeSci is attributed to multiple favorable factors:

  • High-profile support: Public endorsements from industry leaders like Vitalik Buterin and CZ (founder of Binance).

  • Funding Records: DeSci projects have received millions of dollars in investments from top institutions like Binance Labs and a16z.

  • Search interest surges: Google data shows that search interest in 'DeSci' has surpassed that of 'Crypto Gaming' and 'RWA'.

  • Improved Incentive Mechanisms: Directly rewarding contributors through tokens, establishing a transparent and efficient incentive ecosystem.

V. Potential DeSci Projects

The following are DeSci projects ranked by market capitalization, covering multiple fields and showcasing their unique value:

1.$TRAC – OriginTrail

Core Positioning:
OriginTrail is the first project based on decentralized knowledge graph technology (DKG), dedicated to supporting supply chain management, AI data storage, and medical data processing.

Highlights and Application Scenarios:

  • Decentralized Supply Chain: Helping businesses track the production and delivery of goods with full transparency and immutability.

  • Medical Field: Organizing data through knowledge graph technology to optimize patient data storage and sharing.

  • Corporate Support: Collaborating with top companies such as Walmart, GS1, Bureau Veritas, etc.

  • Innovative Driving Force: DKG enables seamless integration of data across industries with AI and machine learning.

Token Functions:

$TRAC tokens serve as circulating currency within the ecosystem, paying for network services and incentivizing nodes.

2.$RIF & $URO

$RIF (Rifampicin) and $URO (Urolithin A) are two tokens closely related to the DeSci narrative, focusing on the biotechnology field, particularly in drug development and anti-aging research.

They are all launched by Pump Science; what highlights does the Pump Science platform have?

  • Integrating $RIF and $URO to create a decentralized platform for integrated biotechnology research, funding, and governance.

  • Eliminating high barriers in traditional medical research, encouraging public and scientific community participation directly.

  • Promoting decentralization in the biotechnology field, providing innovative funding models to support more groundbreaking research.

3.$VITA – VitaDAO

VitaDAO is the first collective funding early-stage longevity research, aiming to extend healthy life and lifespan by raising funds for early research projects and incubating startups for commercialization. It has raised $4.1 million and has support from Pfizer and former Coinbase CTO Balaji Srinivasan.

One of the most important trends is the decentralization and popularization of emerging therapies in the biotechnology field. VitaDAO aims to decentralize these assets, making them widely accessible to people globally.

Over the past few decades, the biopharmaceutical system has largely been monopolized by pharmaceutical companies through patents. If led by VitaDAO, this situation will change as they challenge the traditional biopharmaceutical system's monopoly by decentralizing the acquisition of intellectual property and democratizing ownership more widely.

4.$RSC – ResearchHub

Core Positioning:
ResearchHub is a decentralized scientific research platform, hailed as the 'GitHub of the scientific community'. Its goal is to accelerate scientific progress, breaking traditional academic bottlenecks, and incentivizing research sharing and collaboration through a decentralized reward mechanism.

Highlights and Application Scenarios:

  1. Decentralized Collaboration: Scientists can upload papers, participate in peer reviews and discussions, and promote knowledge dissemination.

  2. Token Incentive Mechanism: Reward contributors through $RSC for activities such as research publication and peer review, enhancing the efficiency and quality of scientific activities.

  3. Community Governance: $RSC token holders can participate in platform decisions, such as feature updates or resource allocation.

  4. Funding Support: Researchers can crowdfund projects directly through ResearchHub, bypassing traditional funding.

    5.$AXGT – AxonDAO

Core Positioning:
AxonDAO focuses on promoting decentralized health research, particularly in the fields of biometrics and AI-driven health diagnostics.

Highlights and Application Scenarios:

  1. Health Data Sharing: Using blockchain technology to allow patients to safely share health data to facilitate research.

  2. AI Personalized Diagnosis: Supporting the development of AI-based personalized medical solutions.

  3. Community Participation in Governance: Users holding $AXGT can vote to determine project priorities, strengthening decentralized autonomy.

Goals:

Integrating AI and medical technology to provide innovative health solutions for patients while promoting the efficient use of global medical data.

6.$HAIR – HairDAO

Core Positioning:
HairDAO focuses on funding the development of new treatments for hair loss, promoting research through community contributions and governance.

Highlights and Application Scenarios:

  • Community Driven: Members holding HAIR tokens can decide funding priorities.

  • Outcome Sharing: Treatment outcomes are shared among all DAO members for profit.

  • Decentralized Funding: Eliminating high barriers in traditional research processes.

Goals:
To prevent hair loss treatments from being monopolized by large corporations through patents.

7.$HPO – Hippocrat

Core Positioning:
Hippocrat is a decentralized healthcare platform that empowers patients to control their health data.

Highlights and Application Scenarios:

  1. Patient Data Sovereignty: Users can decide who to share data with and profit from sharing.

  2. Medical Transparency: Ensuring data privacy while promoting more transparent use of data by research institutions.

  3. Community Incentives: The $HPO token is used to reward participants and promote ecosystem development.

Goals:

Facilitating safer and more efficient medical research through a transparent and controllable data sharing system.

8.$GENOME – GenomesDAO

Core Positioning:
Empowering individuals to control their genetic data, protecting privacy and allowing users to benefit from their data.

Highlights and Application Scenarios:

  • Secure Storage: Genetic data is stored in encrypted form on the blockchain.

  • Privacy Protection: Utilizing zero-knowledge proof technology to ensure users have complete control over their data.

  • Data Monetization: Users can monetize genomic data through secure protocols.

Goals:

Redefining the genetic data economy, empowering individuals.

9.$DNX – Dynex

Core Positioning:
Dynex is a decentralized neuromorphic computing platform, focusing on AI and machine learning applications.

Highlights and Application Scenarios:

  • Breaking the Computational Bottleneck: Utilizing brain-like computing technology to support complex AI models.

  • Transparent Operations: Ensuring transparency in data storage and computation processes based on a blockchain model.

  • Cross-domain Applications: Involving medical imaging processing, climate modeling, and large-scale simulation calculations.

Goals:

Empowering AI computing through blockchain, making high-performance computing resources available to everyone.

10.$LAKE – DataLake

Core Positioning:
DataLake is a patient-centered medical data registry system that uses blockchain to ensure data privacy.

Highlights and Application Scenarios:

  • Patient Sovereignty: Data is controlled by patients who decide the extent of sharing.

  • Incentive Model: Medical institutions receive LAKE token rewards for donating privacy-compliant data.

  • Industry Support: Promoting the progress of pharmaceutical research and facilitating global medical data sharing.

Goals:

Breaking down medical data silos and accelerating pharmaceutical innovation.

11.$GROW – ValleyDAO

Core Positioning:
ValleyDAO is a decentralized autonomous organization dedicated to funding and supporting synthetic biology research that addresses climate change and health challenges.

Highlights and Application Scenarios:

  1. Community Funding: Prioritizing funding for projects that have significant impacts on climate and health through decentralized governance.

  2. Global Open Collaboration: Bringing together researchers and the public to jointly promote the development of sustainable biotechnology.

  3. Innovative Solutions: Focusing on cutting-edge technologies to solve global issues such as biofuels and antibiotic resistance.

Goals:

Providing a new model for global biotechnology research through community-driven and technological innovation.

12.$AIMX – Aimedis

Core Positioning:
Aimedis is a blockchain-based healthcare platform that offers a full range of services from medical record management to telemedicine.

Highlights and Application Scenarios:

  1. Secure Medical Record Management: Patients can securely store and share medical records, improving the efficiency of medical services.

  2. Telemedicine Services: Supporting virtual health consultations and immersive therapies.

  3. Web3 Ecosystem: Combining blockchain technology to create a decentralized service platform for patients and healthcare providers.

Goals:
Revolutionizing healthcare services through technology to enhance medical experience and data management efficiency.

Summary

DeSci is a deep integration of technology and scientific research, entering a golden period of development. Its decentralized philosophy and blockchain technology provide unprecedented momentum for scientific innovation. DeSci is expected to become the next important track for blockchain technology. The projects mentioned above may be potential candidates for tenfold or even hundredfold growth, worthy of close attention!

The future of science may lie in DeSci.