Stock Market: On Wednesday, the three major U.S. stock indexes closed lower, with the Dow Jones Index down 0.30% to 44722.06 points, the S&P 500 Index down 0.38% to 5998.74 points, and the Nasdaq Composite Index down 0.60% to 19060.48 points. The three major A-share indexes fluctuated and strengthened in the afternoon, with the Shanghai Index up 1.53% to 3309.78 points, the Shenzhen Component Index up 2.25% to 10566.10 points, and the ChiNext Index up 2.73% to 2208.78 points.