In summary, Bitcoin investors can judge whether it is time to sell Bitcoin by paying attention to key indicators such as the market value to realized value (MVRV) ratio, the crypto fear and greed index, the number of days to destroy coins (CDD), and the inter-exchange flow pulse (IFP). At the same time, although there are still a lot of unrealized profits in the current market, the MVRV ratio and market sentiment indicators show that Bitcoin has not yet completely reached its peak. But as investors, we should continue to monitor these indicators to grasp the best time to escape the top.