Wall Street's major indexes closed in the red on Friday, extending losses from the previous session. The Dow Jones Industrial Average fell by 0.76%, the S&P 500 lost 0.88%, and the Nasdaq Composite declined by 1.02%. The losses were broad-based, with all 11 sectors in the S&P 500 closing lower. Investors cited concerns about rising interest rates, the war in Ukraine, and the ongoing COVID-19 pandemic as factors contributing to the market's decline.